Within the study period, 87% of all ICU patients had all 12 physiologic measurements available. The APACHE II score is made of 12 physiological variables and 2 disease-related variables. The authors excluded CABG patients because surgical and anesthetic management resulted in falsely elevated APACHE II scores despite a low mortality rate of 1.5%. Initially, the authors did not plan to exclude any patients however, CABG patients (N=785) were later excluded, resulting in a total patient population of 5,030. ![]() The study initially enrolled 5,815 patients admitted to 13 intensive care units in the United States from 1979 to 1982. The Acute Physiology and Chronic Health Evaluation (APACHE II) is a severity score and mortality estimation tool developed from a large sample of ICU patients in the United States.
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